Toxicity evolution of Vipera aspis aspis venom: identification and molecular modeling of a novel phospholipase A(2) heterodimer neurotoxin.

Jan, Virginie; Maroun, R C; Robbe-Vincent, Annie; De Haro, Luc; Choumet, Valérie

Jan, Virginie; Maroun, R C; Robbe-Vincent, Annie; De Haro, Luc; Choumet, Valérie.

Affiliation

Jan V; Unité des Venins, Institut Pasteur, 25 rue du Dr Roux, 75724 Cedex 15, Paris, France. vjan@pasteur.fr

FEBS Lett ; 527(1-3): 263-8, 2002 Sep 11.

Article in En | MEDLINE | ID: mdl-12220671

Subject(s)

Neurotoxins/chemistry; Phospholipases A/chemistry; Viper Venoms/chemistry; Viperidae/physiology; Amino Acid Sequence; Amino Acid Substitution; Animals; Base Sequence; Biological Evolution; Dimerization; Group II Phospholipases A2; Models, Molecular; Molecular Sequence Data; Neurotoxins/genetics; Phospholipases A/genetics; Phospholipases A2; Protein Conformation; Reptilian Proteins; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Viper Venoms/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Phospholipases A / Viper Venoms / Viperidae / Neurotoxins Type of study: Diagnostic_studies Limits: Animals Language: En Journal: FEBS Lett Year: 2002 Type: Article Affiliation country: France

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