Alzheimer's disease is associated with a selective increase in alpha7 nicotinic acetylcholine receptor immunoreactivity in astrocytes.

Teaktong, Thanasak; Graham, Alison; Court, Jennifer; Perry, Robert; Jaros, Evelyn; Johnson, Mary; Hall, Ros; Perry, Elaine

Teaktong, Thanasak; Graham, Alison; Court, Jennifer; Perry, Robert; Jaros, Evelyn; Johnson, Mary; Hall, Ros; Perry, Elaine.

Affiliation

Teaktong T; MRC Building, Centre Development in Clinical Brain Aging, Newcastle General Hospital, Newcastle Upon Tyne, UK.

Glia ; 41(2): 207-11, 2003 Jan 15.

Article in En | MEDLINE | ID: mdl-12509811

Subject(s)

Alzheimer Disease/metabolism; Astrocytes/metabolism; Entorhinal Cortex/metabolism; Hippocampus/metabolism; Receptors, Nicotinic/metabolism; Up-Regulation/physiology; Aged; Aged, 80 and over; Alzheimer Disease/pathology; Alzheimer Disease/physiopathology; Astrocytes/cytology; Calcium/metabolism; Entorhinal Cortex/pathology; Entorhinal Cortex/physiopathology; Hippocampus/pathology; Hippocampus/physiopathology; Homeostasis/physiology; Humans; Immunohistochemistry; Lewy Body Disease/metabolism; Lewy Body Disease/pathology; Lewy Body Disease/physiopathology; Nitric Oxide/metabolism; Plaque, Amyloid/metabolism; alpha7 Nicotinic Acetylcholine Receptor

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Collection: 01-internacional Database: MEDLINE Main subject: Up-Regulation / Astrocytes / Receptors, Nicotinic / Entorhinal Cortex / Alzheimer Disease / Hippocampus Type of study: Risk_factors_studies Limits: Aged / Aged80 / Humans Language: En Journal: Glia Journal subject: NEUROLOGIA Year: 2003 Type: Article Affiliation country: United kingdom

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