Sodium intake and blood pressure in healthy individuals.
J Hypertens
; 21(2): 289-94, 2003 Feb.
Article
in En
| MEDLINE
| ID: mdl-12569258
ABSTRACT
OBJECTIVE:
To investigate further the relationships between blood pressure and sodium intake, which have been claimed to exist, but have not been clearly established, in epidemiological studies. DESIGN ANDPARTICIPANTS:
A 2-year follow up study of a cohort of 296 healthy volunteers working in the same company.RESULTS:
Consistent with previously reported findings, covariance analysis in the entire population, including multivariate analysis to examine the potential influence of confounding variables, failed to identify a significant relationship between blood pressure and sodium intake or between their respective changes within 2 years. To test the hypothesis of a heterogeneous distribution of salt sensitivity, we calculated the statistical dependence between blood pressure and sodium intake using the coefficient analysis that quantifies the prevalence of a statistical link between two variables. A significant dependence (P < 0.05) between diastolic (DBP) or systolic (SBP) blood pressure and sodium intake was found in 16 and 5% of the participants, respectively. The analysis of the 2-year changes in blood pressure and sodium intake reinforced our findings. Our finding of a relationship between blood pressure and sodium intake in only a few individuals may explain the lack of a global relationship between these two variables investigated by the covariance analysis in our study.(Rho)CONCLUSION:
Our results suggest that 5-16% of healthy individuals have a 'salt-dependent blood pressure' and might benefit from a reduction in dietary salt intake.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Blood Pressure
/
Sodium, Dietary
Type of study:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Adult
/
Humans
/
Middle aged
Language:
En
Journal:
J Hypertens
Year:
2003
Type:
Article
Affiliation country:
France