4-Hydroxymethyl- and 4-methoxymethylfuro[2,3-h]quinolin-2(1H)-ones: synthesis and biological properties.

Chilin, Adriana; Marzano, Cristina; Baccichetti, Francarosa; Simonato, Morena; Guiotto, Adriano

Chilin, Adriana; Marzano, Cristina; Baccichetti, Francarosa; Simonato, Morena; Guiotto, Adriano.

Affiliation

Chilin A; Department of Pharmaceutical Sciences, University of Padova, Via Francesco Marzolo 5, I-35131, Padova, Italy. adriana.chilin@unipd.it

Bioorg Med Chem ; 11(7): 1311-8, 2003 Apr 03.

Article in En | MEDLINE | ID: mdl-12628658

Subject(s)

Antineoplastic Agents/chemical synthesis; Antineoplastic Agents/pharmacology; Enzyme Inhibitors/chemical synthesis; Enzyme Inhibitors/pharmacology; Furans/chemical synthesis; Furans/pharmacology; Quinolones/chemical synthesis; Quinolones/pharmacology; Topoisomerase II Inhibitors; Animals; Antineoplastic Agents/metabolism; Carcinoma, Ehrlich Tumor; Cattle; DNA/metabolism; DNA/radiation effects; Dermatitis, Phototoxic/pathology; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors/metabolism; Escherichia coli/drug effects; Escherichia coli/genetics; Guinea Pigs; HeLa Cells; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mutagens/chemical synthesis; Mutagens/metabolism; Mutagens/pharmacology; Photochemistry; Plasmids/drug effects; Plasmids/genetics; Tumor Cells, Cultured; Ultraviolet Rays

Search on Google

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Quinolones / Enzyme Inhibitors / Topoisomerase II Inhibitors / Furans / Antineoplastic Agents Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2003 Type: Article Affiliation country: Italy

Search on Google

XML

PubMed Links