GW274150, a potent and highly selective inhibitor of iNOS, reduces experimental renal ischemia/reperfusion injury.

Chatterjee, Prabal K; Patel, Nimesh S A; Sivarajah, Ahila; Kvale, Espen O; Dugo, Laura; Cuzzocrea, Salvatore; Brown, Paul A J; Stewart, Keith N; Mota-Filipe, Helder; Britti, Domenico; Yaqoob, Muhammad M; Thiemermann, Christoph

Chatterjee, Prabal K; Patel, Nimesh S A; Sivarajah, Ahila; Kvale, Espen O; Dugo, Laura; Cuzzocrea, Salvatore; Brown, Paul A J; Stewart, Keith N; Mota-Filipe, Helder; Britti, Domenico; Yaqoob, Muhammad M; Thiemermann, Christoph.

Affiliation

Chatterjee PK; Department of Experimental Medicine and Nephrology, The William Harvey Research Institute, Queen Mary, University of London, Charterhouse Square, London, United Kingdom. p.k.chatterjee@qmul.ac.uk

Kidney Int ; 63(3): 853-65, 2003 Mar.

Article in En | MEDLINE | ID: mdl-12631066

Subject(s)

Enzyme Inhibitors/pharmacology; Kidney Diseases/drug therapy; Nitric Oxide Synthase/antagonists & inhibitors; Reperfusion Injury/drug therapy; Sulfides/pharmacology; Tyrosine/analogs & derivatives; Animals; Creatinine/blood; Kidney/enzymology; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Nitric Oxide/blood; Nitric Oxide Synthase/genetics; Nitric Oxide Synthase Type II; Peroxidase/metabolism; Poly Adenosine Diphosphate Ribose/metabolism; Rats; Rats, Wistar; Tyrosine/metabolism; Urea/blood

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Collection: 01-internacional Database: MEDLINE Main subject: Sulfides / Tyrosine / Reperfusion Injury / Nitric Oxide Synthase / Enzyme Inhibitors / Kidney Diseases Type of study: Prognostic_studies Limits: Animals Language: En Journal: Kidney Int Year: 2003 Type: Article Affiliation country: United kingdom

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