Platelet glycoprotein IIb/IIIa receptor blockade improves vascular nitric oxide bioavailability in patients with coronary artery disease.

Heitzer, Thomas; Ollmann, Isabel; Köke, Katharina; Meinertz, Thomas; Munzel, Thomas

Heitzer, Thomas; Ollmann, Isabel; Köke, Katharina; Meinertz, Thomas; Munzel, Thomas.

Affiliation

Heitzer T; Universitätsklinikum Hamburg-Eppendorf, Medizinische Klinik III, Abteilung Kardiologie und Angiologie, Martinistrasse 52, 20246 Hamburg, Germany. heitzer@uke.uni-hamburg.de

Circulation ; 108(5): 536-41, 2003 Aug 05.

Article in En | MEDLINE | ID: mdl-12874186

Subject(s)

Coronary Artery Disease/physiopathology; Endothelium, Vascular/physiopathology; Nitric Oxide/metabolism; Platelet Glycoprotein GPIIb-IIIa Complex/antagonists & inhibitors; Vasomotor System/physiopathology; Acetylcholine/pharmacology; Biological Availability; Blood Flow Velocity/drug effects; Blood Platelets/drug effects; Blood Platelets/metabolism; Coronary Artery Disease/drug therapy; Endothelium, Vascular/drug effects; Endothelium, Vascular/metabolism; Enzyme Inhibitors/pharmacology; Eptifibatide; Forearm/blood supply; Humans; Male; Middle Aged; Nitric Oxide Donors/pharmacology; Peptides/pharmacology; Platelet Aggregation Inhibitors/pharmacology; Plethysmography; Tirofiban; Tyrosine/analogs & derivatives; Tyrosine/pharmacology; Vasodilation/drug effects; Vasodilator Agents/pharmacology; Vasomotor System/drug effects; omega-N-Methylarginine/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Vasomotor System / Coronary Artery Disease / Endothelium, Vascular / Platelet Glycoprotein GPIIb-IIIa Complex / Nitric Oxide Limits: Humans / Male / Middle aged Language: En Journal: Circulation Year: 2003 Type: Article Affiliation country: Germany

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