Phorbol ester activation of the protein kinase C pathway inhibits gonadotropin-releasing hormone gene expression.

Bruder, J M; Krebs, W D; Nett, T M; Wierman, M E

Bruder, J M; Krebs, W D; Nett, T M; Wierman, M E.

Affiliation

Bruder JM; Department of Medicine, University of Colorado Health Sciences Center, Denver 80220.

Endocrinology ; 131(6): 2552-8, 1992 Dec.

Article in En | MEDLINE | ID: mdl-1446598

Subject(s)

Gene Expression/drug effects; Gonadotropin-Releasing Hormone/genetics; Protein Kinase C/metabolism; Tetradecanoylphorbol Acetate/pharmacology; Alkaloids/pharmacology; Animals; Cell Line; DNA Probes; Dose-Response Relationship, Drug; Enzyme Activation/drug effects; Gonadotropin-Releasing Hormone/metabolism; Kinetics; Mice; Nucleic Acid Hybridization; Protein Kinase C/antagonists & inhibitors; Rats; Staurosporine; Tetradecanoylphorbol Acetate/administration & dosage

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Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinase C / Tetradecanoylphorbol Acetate / Gene Expression / Gonadotropin-Releasing Hormone Limits: Animals Language: En Journal: Endocrinology Year: 1992 Type: Article

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