Prostaglandin E2 stimulates the growth of colon cancer cells via induction of amphiregulin.

Shao, Jinyi; Lee, Sean B; Guo, Huiping; Evers, B Mark; Sheng, Hongmiao

Shao, Jinyi; Lee, Sean B; Guo, Huiping; Evers, B Mark; Sheng, Hongmiao.

Affiliation

Shao J; Department of Surgery, University of Texas Medical Branch, Galveston, Texas 77555, USA.

Cancer Res ; 63(17): 5218-23, 2003 Sep 01.

Article in En | MEDLINE | ID: mdl-14500348

Subject(s)

Colonic Neoplasms/pathology; Dinoprostone/pharmacology; Glycoproteins/biosynthesis; Intercellular Signaling Peptides and Proteins/biosynthesis; Amphiregulin; Cell Division/drug effects; Colonic Neoplasms/genetics; Colonic Neoplasms/metabolism; Cyclic AMP/physiology; Cyclic AMP-Dependent Protein Kinases/physiology; Cyclooxygenase 2; Drug Synergism; EGF Family of Proteins; Gene Expression Regulation, Neoplastic/drug effects; Gene Expression Regulation, Neoplastic/physiology; Glycoproteins/genetics; Humans; Intercellular Signaling Peptides and Proteins/genetics; Isoenzymes/metabolism; Membrane Proteins; Promoter Regions, Genetic/drug effects; Prostaglandin-Endoperoxide Synthases/metabolism; Signal Transduction/drug effects; Signal Transduction/physiology; Transforming Growth Factor alpha/pharmacology; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Glycoproteins / Dinoprostone / Colonic Neoplasms / Intercellular Signaling Peptides and Proteins Limits: Humans Language: En Journal: Cancer Res Year: 2003 Type: Article Affiliation country: United States

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