Beta 1-adrenergic receptor polymorphisms confer differential function and predisposition to heart failure.

Mialet Perez, Jeanne; Rathz, Deborah A; Petrashevskaya, Natalia N; Hahn, Harvey S; Wagoner, Lynne E; Schwartz, Arnold; Dorn, Gerald W; Liggett, Stephen B

Mialet Perez, Jeanne; Rathz, Deborah A; Petrashevskaya, Natalia N; Hahn, Harvey S; Wagoner, Lynne E; Schwartz, Arnold; Dorn, Gerald W; Liggett, Stephen B.

Affiliation

Mialet Perez J; Department of Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, USA.

Nat Med ; 9(10): 1300-5, 2003 Oct.

Article in En | MEDLINE | ID: mdl-14502278

Subject(s)

Cardiac Output, Low/genetics; Genetic Predisposition to Disease; Polymorphism, Genetic; Receptors, Adrenergic, beta-1/genetics; Receptors, Adrenergic, beta-1/metabolism; Adrenergic beta-Antagonists/metabolism; Adrenergic beta-Antagonists/therapeutic use; Animals; Arginine/metabolism; Cardiac Output, Low/drug therapy; Cardiac Output, Low/metabolism; Echocardiography; Glycine/metabolism; Humans; Mice; Mice, Transgenic; Myocardial Contraction/physiology; Phenotype

Search on Google

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Polymorphism, Genetic / Cardiac Output, Low / Receptors, Adrenergic, beta-1 / Genetic Predisposition to Disease Limits: Animals / Humans Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2003 Type: Article Affiliation country: United States

Search on Google

XML

PubMed Links