Intrathecal synthesis of monocyte chemoattractant protein-1 (MCP-1) in amyotrophic lateral sclerosis: further evidence for microglial activation in neurodegeneration.

Wilms, H; Sievers, J; Dengler, R; Bufler, J; Deuschl, G; Lucius, R

Wilms, H; Sievers, J; Dengler, R; Bufler, J; Deuschl, G; Lucius, R.

Affiliation

Wilms H; Klinik für Neurologie, Christian-Albrechts-Universität Kiel, Niemannsweg 147, 24105 Kiel, Germany. h.wilms@neurologie.uni-kiel.de

J Neuroimmunol ; 144(1-2): 139-42, 2003 Nov.

Article in En | MEDLINE | ID: mdl-14597108

Subject(s)

Amyotrophic Lateral Sclerosis/cerebrospinal fluid; Amyotrophic Lateral Sclerosis/pathology; Cerebrospinal Fluid Proteins/biosynthesis; Chemokine CCL2/biosynthesis; Chemokine CCL2/cerebrospinal fluid; Microglia/metabolism; Microglia/pathology; Age of Onset; Aged; Amyotrophic Lateral Sclerosis/immunology; Analysis of Variance; Cell Movement/immunology; Cerebrospinal Fluid Proteins/blood; Cerebrospinal Fluid Proteins/cerebrospinal fluid; Chemokine CCL2/blood; Humans; Microglia/immunology; Middle Aged; Regression Analysis; Statistics, Nonparametric; Up-Regulation/immunology

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Collection: 01-internacional Database: MEDLINE Main subject: Cerebrospinal Fluid Proteins / Microglia / Chemokine CCL2 / Amyotrophic Lateral Sclerosis Type of study: Diagnostic_studies Limits: Aged / Humans / Middle aged Language: En Journal: J Neuroimmunol Year: 2003 Type: Article Affiliation country: Germany

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