Conditional disruption of IkappaB kinase 2 fails to prevent obesity-induced insulin resistance.

Röhl, Mathias; Pasparakis, Manolis; Baudler, Stephanie; Baumgartl, Julia; Gautam, Dinesh; Huth, Marion; De Lorenzi, Rossana; Krone, Wilhelm; Rajewsky, Klaus; Brüning, Jens C

Röhl, Mathias; Pasparakis, Manolis; Baudler, Stephanie; Baumgartl, Julia; Gautam, Dinesh; Huth, Marion; De Lorenzi, Rossana; Krone, Wilhelm; Rajewsky, Klaus; Brüning, Jens C.

Affiliation

Röhl M; Klinik II und Poliklinik für Innere Medizin der Universität zu Köln and Center for Molecular Medicine Cologne, Germany.

J Clin Invest ; 113(3): 474-81, 2004 Feb.

Article in En | MEDLINE | ID: mdl-14755344

Subject(s)

Insulin Resistance/physiology; Obesity/enzymology; Protein Serine-Threonine Kinases/metabolism; Animals; Aurothioglucose/metabolism; I-kappa B Kinase; Insulin/metabolism; Mice; Muscle, Skeletal/enzymology; Muscle, Skeletal/metabolism; Obesity/metabolism; Protein Serine-Threonine Kinases/genetics; Signal Transduction/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Insulin Resistance / Protein Serine-Threonine Kinases / Obesity Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Clin Invest Year: 2004 Type: Article Affiliation country: Germany

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