Failure of gamma-hydroxybutyric acid both to increase neuroactive steroid concentrations in adrenalectomized-orchiectomized rats and to induce tolerance to its steroidogenic effect in intact animals.

Porcu, Patrizia; Sogliano, Cristiana; Ibba, Cristina; Piredda, Massimo; Tocco, Silvia; Marra, Carla; Purdy, Robert H; Biggio, Giovanni; Concas, Alessandra

Porcu, Patrizia; Sogliano, Cristiana; Ibba, Cristina; Piredda, Massimo; Tocco, Silvia; Marra, Carla; Purdy, Robert H; Biggio, Giovanni; Concas, Alessandra.

Affiliation

Porcu P; Department of Experimental Biology, Center of Excellence for Neurobiology of Dependence, University of Cagliari, Cagliari, Italy.

Brain Res ; 1012(1-2): 160-8, 2004 Jun 25.

Article in En | MEDLINE | ID: mdl-15158173

Subject(s)

Adrenalectomy; Cerebral Cortex/drug effects; Hydroxybutyrates/pharmacology; Orchiectomy; Steroids/metabolism; Animals; Cerebral Cortex/metabolism; Drug Tolerance/physiology; Male; Rats; Rats, Sprague-Dawley; Steroids/blood

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Collection: 01-internacional Database: MEDLINE Main subject: Steroids / Orchiectomy / Cerebral Cortex / Adrenalectomy / Hydroxybutyrates Limits: Animals Language: En Journal: Brain Res Year: 2004 Type: Article Affiliation country: Italy

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