Clinical inhibition of the seven-transmembrane thrombin receptor (PAR1) by intravenous aprotinin during cardiothoracic surgery.

Day, J R S; Punjabi, P P; Randi, A M; Haskard, D O; Landis, R C; Taylor, K M

Day, J R S; Punjabi, P P; Randi, A M; Haskard, D O; Landis, R C; Taylor, K M.

Affiliation

Day JR; British Heart Foundation Cardiac Surgery Unit, Eric Bywaters Centre, Imperial College, London W12 0NN, UK. j.day@imperial.ac.uk

Circulation ; 110(17): 2597-600, 2004 Oct 26.

Article in En | MEDLINE | ID: mdl-15262827

Subject(s)

Aprotinin/therapeutic use; Cardiopulmonary Bypass; Receptor, PAR-1/antagonists & inhibitors; Humans; Thrombin/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Cardiopulmonary Bypass / Aprotinin / Receptor, PAR-1 Type of study: Clinical_trials Limits: Humans Language: En Journal: Circulation Year: 2004 Type: Article Affiliation country: United kingdom

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