The IL-27 receptor (WSX-1) is an inhibitor of innate and adaptive elements of type 2 immunity.

Artis, David; Villarino, Alejandro; Silverman, Michael; He, Weimian; Thornton, Elizabeth M; Mu, Sharon; Summer, Shamin; Covey, Todd M; Huang, Elaine; Yoshida, Hiroki; Koretzky, Gary; Goldschmidt, Michael; Wu, Gary D; de Sauvage, Fred; Miller, Hugh R P; Saris, Christiaan J M; Scott, Phillip; Hunter, Christopher A

Artis, David; Villarino, Alejandro; Silverman, Michael; He, Weimian; Thornton, Elizabeth M; Mu, Sharon; Summer, Shamin; Covey, Todd M; Huang, Elaine; Yoshida, Hiroki; Koretzky, Gary; Goldschmidt, Michael; Wu, Gary D; de Sauvage, Fred; Miller, Hugh R P; Saris, Christiaan J M; Scott, Phillip; Hunter, Christopher A.

Affiliation

Artis D; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

J Immunol ; 173(9): 5626-34, 2004 Nov 01.

Article in En | MEDLINE | ID: mdl-15494513

Subject(s)

Down-Regulation/immunology; Interleukins/physiology; Receptors, Cytokine/physiology; Suppressor Factors, Immunologic/physiology; Th2 Cells/immunology; Animals; Cytokines/biosynthesis; Goblet Cells/immunology; Goblet Cells/pathology; Immunity, Innate/genetics; Immunity, Mucosal/genetics; Interferon-gamma/antagonists & inhibitors; Interferon-gamma/biosynthesis; Interleukins/biosynthesis; Interleukins/genetics; Intestinal Diseases, Parasitic/genetics; Intestinal Diseases, Parasitic/immunology; Intestinal Diseases, Parasitic/pathology; Mastocytosis/genetics; Mastocytosis/immunology; Mastocytosis/pathology; Mice; Mice, Inbred C57BL; Mice, Knockout; RNA, Messenger/biosynthesis; Receptors, Cytokine/deficiency; Receptors, Cytokine/genetics; Receptors, Interleukin; Suppressor Factors, Immunologic/deficiency; Suppressor Factors, Immunologic/genetics; Th2 Cells/metabolism; Th2 Cells/parasitology; Trichuriasis/genetics; Trichuriasis/immunology; Trichuriasis/parasitology; Trichuriasis/pathology; Trichuris/growth & development; Trichuris/immunology

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Collection: 01-internacional Database: MEDLINE Main subject: Down-Regulation / Interleukins / Suppressor Factors, Immunologic / Receptors, Cytokine / Th2 Cells Type of study: Prognostic_studies Language: En Journal: J Immunol Year: 2004 Type: Article Affiliation country: United States

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