A lentiviral vector encoding the human Wiskott-Aldrich syndrome protein corrects immune and cytoskeletal defects in WASP knockout mice.

Charrier, S; Stockholm, D; Seye, K; Opolon, P; Taveau, M; Gross, D-A; Bucher-Laurent, S; Delenda, C; Vainchenker, W; Danos, O; Galy, A

Charrier, S; Stockholm, D; Seye, K; Opolon, P; Taveau, M; Gross, D-A; Bucher-Laurent, S; Delenda, C; Vainchenker, W; Danos, O; Galy, A.

Affiliation

Charrier S; Genethon UMR CNRS 8115, Evry, France.

Gene Ther ; 12(7): 597-606, 2005 Apr.

Article in En | MEDLINE | ID: mdl-15616597

Subject(s)

Genetic Therapy/methods; Genetic Vectors/therapeutic use; HIV-1/genetics; Proteins/genetics; Wiskott-Aldrich Syndrome/therapy; Animals; Bone Marrow Transplantation/methods; Colitis/therapy; Dendritic Cells/metabolism; Dendritic Cells/ultrastructure; Gene Expression; Genetic Therapy/adverse effects; Humans; Mice; Mice, Knockout; Proteins/metabolism; RNA, Messenger/genetics; T-Lymphocytes/immunology; Transduction, Genetic; Wiskott-Aldrich Syndrome/immunology; Wiskott-Aldrich Syndrome/metabolism; Wiskott-Aldrich Syndrome Protein

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Collection: 01-internacional Database: MEDLINE Main subject: Wiskott-Aldrich Syndrome / Genetic Therapy / Proteins / HIV-1 / Genetic Vectors Limits: Animals / Humans Language: En Journal: Gene Ther Journal subject: GENETICA MEDICA / TERAPEUTICA Year: 2005 Type: Article Affiliation country: France

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