Population pharmacokinetics of motexafin gadolinium in adults with brain metastases or glioblastoma multiforme.

Miles, Dale R; Smith, Jennifer A; Phan, See-Chun; Hutcheson, Sammy J; Renschler, Markus F; Ford, Judith M; Boswell, Garry W

Miles, Dale R; Smith, Jennifer A; Phan, See-Chun; Hutcheson, Sammy J; Renschler, Markus F; Ford, Judith M; Boswell, Garry W.

Affiliation

Miles DR; Pharmacyclics Inc, 995 E. Arques Avenue, Sunnyvale, CA 94085, USA.

J Clin Pharmacol ; 45(3): 299-312, 2005 Mar.

Article in En | MEDLINE | ID: mdl-15703365

Subject(s)

Antineoplastic Agents/pharmacokinetics; Metalloporphyrins/pharmacokinetics; Models, Biological; Adult; Age Factors; Aged; Aged, 80 and over; Alkaline Phosphatase/metabolism; Anticonvulsants/pharmacology; Antineoplastic Agents/blood; Brain Neoplasms/blood; Brain Neoplasms/drug therapy; Brain Neoplasms/metabolism; Clinical Trials as Topic; Creatinine/blood; Data Interpretation, Statistical; Female; Follow-Up Studies; Glioblastoma/blood; Glioblastoma/drug therapy; Glioblastoma/metabolism; Humans; Male; Metabolic Clearance Rate; Metalloporphyrins/blood; Middle Aged; Neoplasm Metastasis; Phenytoin/pharmacology; Sex Factors; Software

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Collection: 01-internacional Database: MEDLINE Main subject: Metalloporphyrins / Models, Biological / Antineoplastic Agents Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: J Clin Pharmacol Year: 2005 Type: Article Affiliation country: United States

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