Albendazole repeated administration induces cytochromes P4501A and accelerates albendazole deactivation in mouflon (Ovis musimon).

Velík, J; Szotáková, B; Baliharová, V; Lamka, J; Savlík, M; Wsól, V; Snejdrová, E; Skálová, L

Velík, J; Szotáková, B; Baliharová, V; Lamka, J; Savlík, M; Wsól, V; Snejdrová, E; Skálová, L.

Affiliation

Velík J; Faculty of Pharmacy, Department of Biochemical Sciences, Charles University, Heyrovského 1203, Hradec Králové, Czech Republic.

Res Vet Sci ; 78(3): 255-63, 2005 Jun.

Article in En | MEDLINE | ID: mdl-15766946

Subject(s)

Albendazole/pharmacology; Albendazole/pharmacokinetics; Anthelmintics/pharmacology; Anthelmintics/pharmacokinetics; Cytochrome P-450 Enzyme System/metabolism; Sheep, Domestic/metabolism; Albendazole/administration & dosage; Animals; Anthelmintics/administration & dosage; Enzyme Activation/drug effects; Female; Intestine, Small/enzymology; Liver/enzymology

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Collection: 01-internacional Database: MEDLINE Main subject: Albendazole / Cytochrome P-450 Enzyme System / Sheep, Domestic / Anthelmintics Limits: Animals Language: En Journal: Res Vet Sci Year: 2005 Type: Article Affiliation country: Czech Republic

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