Mefloquine inhibits cholinesterases at the mouse neuromuscular junction.

McArdle, Joseph J; Sellin, Lawrence C; Coakley, Kathleen M; Potian, Joseph G; Quinones-Lopez, Mary C; Rosenfeld, Clint A; Sultatos, Lester G; Hognason, Kormakur

McArdle, Joseph J; Sellin, Lawrence C; Coakley, Kathleen M; Potian, Joseph G; Quinones-Lopez, Mary C; Rosenfeld, Clint A; Sultatos, Lester G; Hognason, Kormakur.

Affiliation

McArdle JJ; Department of Pharmacology and Physiology, New Jersey Medical School and Graduate School of Biomedical Sciences, UMDNJ, 185 South Orange Avenue, Newark, NJ 07101-1709, USA. mcardle@umdnj.edu

Neuropharmacology ; 49(8): 1132-9, 2005 Dec.

Article in En | MEDLINE | ID: mdl-16081111

Subject(s)

Antimalarials/pharmacology; Cholinesterase Inhibitors; Mefloquine/pharmacology; Neuromuscular Junction/drug effects; Acetylcholinesterase/genetics; Acetylcholinesterase/physiology; Animals; Butyrylcholinesterase/metabolism; Dose-Response Relationship, Drug; Electrophysiology; Humans; Membrane Potentials/drug effects; Mice; Mice, Knockout; Motor Endplate/drug effects; Parasympathetic Nervous System/drug effects; Physostigmine/pharmacology; Synapses/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Mefloquine / Cholinesterase Inhibitors / Antimalarials / Neuromuscular Junction Limits: Animals / Humans Language: En Journal: Neuropharmacology Year: 2005 Type: Article Affiliation country: United States

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