A method for trapping intermediates of polyketide biosynthesis with a nonhydrolyzable malonyl-coenzyme A analogue.

Spiteller, Dieter; Waterman, Claire L; Spencer, Jonathan B

Spiteller, Dieter; Waterman, Claire L; Spencer, Jonathan B.

Affiliation

Spiteller D; Department of Biochemistry, University of Cambridge, UK.

Angew Chem Int Ed Engl ; 44(43): 7079-82, 2005 Nov 04.

Article in En | MEDLINE | ID: mdl-16208728

Subject(s)

Macrolides/metabolism; Malonyl Coenzyme A/analogs & derivatives; Malonyl Coenzyme A/metabolism; Macrolides/chemistry; Malonyl Coenzyme A/chemistry; Molecular Structure; Polyketide Synthases/chemistry; Polyketide Synthases/metabolism; Streptomyces/enzymology; Time Factors

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Collection: 01-internacional Database: MEDLINE Main subject: Macrolides / Malonyl Coenzyme A Language: En Journal: Angew Chem Int Ed Engl Year: 2005 Type: Article Affiliation country: United kingdom

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