Sevelamer prevents uremia-enhanced atherosclerosis progression in apolipoprotein E-deficient mice.

Phan, Olivier; Ivanovski, Ognen; Nguyen-Khoa, Thao; Mothu, Nadya; Angulo, Jesus; Westenfeld, Ralf; Ketteler, Markus; Meert, Natalie; Maizel, Julien; Nikolov, Igor G; Vanholder, Raymond; Lacour, Bernard; Drüeke, Tilman B; Massy, Ziad A

Phan, Olivier; Ivanovski, Ognen; Nguyen-Khoa, Thao; Mothu, Nadya; Angulo, Jesus; Westenfeld, Ralf; Ketteler, Markus; Meert, Natalie; Maizel, Julien; Nikolov, Igor G; Vanholder, Raymond; Lacour, Bernard; Drüeke, Tilman B; Massy, Ziad A.

Affiliation

Phan O; INSERM Unit 507, Necker Hospital, Paris, France.

Circulation ; 112(18): 2875-82, 2005 Nov 01.

Article in En | MEDLINE | ID: mdl-16267260

Subject(s)

Apolipoproteins E/deficiency; Atherosclerosis/physiopathology; Polyamines/therapeutic use; Uremia/complications; Animals; Apolipoproteins E/genetics; Atherosclerosis/etiology; Atherosclerosis/metabolism; Atherosclerosis/pathology; Collagen/metabolism; Disease Progression; Macrophages/pathology; Mice; Mice, Knockout; Monocytes/pathology; Placebos; Sevelamer; Tyrosine/analogs & derivatives; Tyrosine/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Apolipoproteins E / Polyamines / Uremia / Atherosclerosis Type of study: Etiology_studies Limits: Animals Language: En Journal: Circulation Year: 2005 Type: Article Affiliation country: France

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