Morpheaform extra-ocular sebaceous carcinoma.
J Surg Oncol
; 92(4): 344-6, 2005 Dec 15.
Article
in En
| MEDLINE
| ID: mdl-16299801
ABSTRACT
BACKGROUND:
Sebaceous carcinoma is an unusual, aggressive, malignant tumor derived from the epithelium of sebaceous glands. It may arise in ocular or extra-ocular sites and is often evident as an ulcerated or non-ulcerated cystic nodule measuring up to 8 cm in diameter. A significant number of extra-ocular sebaceous carcinomas have been associated with metastases and high mortality rate. METHODS ANDRESULTS:
We reviewed the literature in the context of our report of a 68-year-old woman who had a morpheaform plaque of the upper lip of 15 years duration, extending into the left naso-genal groove, which histologically also showed marked stromal fibrosis. Three years after excision, there were no signs of recurrence or metastases.CONCLUSIONS:
This patient is unusual in clinical and histologic pattern, as a morpheaform appearance has only been described previously in only one sebaceous carcinoma. In addition, no metastatic disease 15 years after tumor onset is a fortunate and remarkable feature.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Scleroderma, Localized
/
Sebaceous Gland Neoplasms
/
Adenocarcinoma, Sebaceous
/
Lip
Limits:
Aged
/
Female
/
Humans
Language:
En
Journal:
J Surg Oncol
Year:
2005
Type:
Article
Affiliation country:
Italy