Plasma level of a 5-fluorouracil metabolite, fluoro-beta-alanine correlates with dihydropyrimidine dehydrogenase activity of peripheral blood mononuclear cells in 5-fluorouracil treated patients.

Furuhata, T; Kawakami, M; Okita, K; Kimura, Y; Kihara, C; Tsuruma, T; Ohmura, T; Yamaguchi, K; Hata, F; Katsuramaki, T; Sasaki, K; Hirata, K

Furuhata, T; Kawakami, M; Okita, K; Kimura, Y; Kihara, C; Tsuruma, T; Ohmura, T; Yamaguchi, K; Hata, F; Katsuramaki, T; Sasaki, K; Hirata, K.

Affiliation

Furuhata T; First Department of Surgery, Sapporo Medical University, Sapporo, Japan. furuhata@sapmed.ac.jp

J Exp Clin Cancer Res ; 25(1): 79-82, 2006 Mar.

Article in En | MEDLINE | ID: mdl-16761622

Subject(s)

Colorectal Neoplasms/drug therapy; Colorectal Neoplasms/surgery; Fluorouracil/blood; Fluorouracil/therapeutic use; Leukocytes, Mononuclear/cytology; Aged; Alanine/analogs & derivatives; Alanine/chemistry; Chromatography, High Pressure Liquid; Combined Modality Therapy; Dihydrouracil Dehydrogenase (NADP)/metabolism; Female; Humans; Leukocytes, Mononuclear/metabolism; Male; Middle Aged; o-Phthalaldehyde/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Leukocytes, Mononuclear / Colorectal Neoplasms / Fluorouracil Type of study: Prognostic_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: J Exp Clin Cancer Res Year: 2006 Type: Article Affiliation country: Japan

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