Linarin, a selective acetylcholinesterase inhibitor from Mentha arvensis.

Oinonen, Päivi P; Jokela, Jouni K; Hatakka, Annele I; Vuorela, Pia M

Oinonen, Päivi P; Jokela, Jouni K; Hatakka, Annele I; Vuorela, Pia M.

Affiliation

Oinonen PP; Drug Discovery and Development Technology Center, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland. pmpti005@chiangmai.ac.th

Fitoterapia ; 77(6): 429-34, 2006 Sep.

Article in En | MEDLINE | ID: mdl-16815640

ABSTRACT

ABSTRACT

Linarin (acacetin-7-O-beta-d-rutinoside) from the flower extract of Mentha arvensis showed selective dose dependent inhibitory effect on acetylcholinesterase.

Subject(s)

Acetylcholinesterase/chemistry; Cholinesterase Inhibitors/pharmacology; Glycosides/pharmacology; Mentha; Phytotherapy; Cholinesterase Inhibitors/administration & dosage; Cholinesterase Inhibitors/therapeutic use; Dose-Response Relationship, Drug; Flowers; Glycosides/administration & dosage; Glycosides/therapeutic use; Humans; Plant Extracts/administration & dosage; Plant Extracts/pharmacology; Plant Extracts/therapeutic use

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Collection: 01-internacional Database: MEDLINE Main subject: Acetylcholinesterase / Cholinesterase Inhibitors / Mentha / Glycosides / Phytotherapy Limits: Humans Language: En Journal: Fitoterapia Year: 2006 Type: Article Affiliation country: Finland

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