Soluble Abeta and cognitive function in aged F-344 rats and Tg2576 mice.

Lindner, Mark D; Hogan, John B; Krause, Rudolph G; Machet, Frederic; Bourin, Clotilde; Hodges, Donald B; Corsa, Jason A; Barten, Donna M; Toyn, Jeremy H; Stock, David A; Rose, Gregory M; Gribkoff, Valentin K

Lindner, Mark D; Hogan, John B; Krause, Rudolph G; Machet, Frederic; Bourin, Clotilde; Hodges, Donald B; Corsa, Jason A; Barten, Donna M; Toyn, Jeremy H; Stock, David A; Rose, Gregory M; Gribkoff, Valentin K.

Affiliation

Lindner MD; Neuroscience Drug Discovery, Bristol-Myers Squibb Pharmaceutical Research Institute, 5 Research Parkway, Wallingford, CT 06492, USA. Mark.Linder@BMS.com

Behav Brain Res ; 173(1): 62-75, 2006 Oct 02.

Article in En | MEDLINE | ID: mdl-16828889

Subject(s)

Aging/metabolism; Amyloid beta-Peptides/metabolism; Brain/metabolism; Maze Learning/physiology; Acoustic Stimulation; Amyloid beta-Peptides/chemistry; Amyloid beta-Protein Precursor/genetics; Analysis of Variance; Animals; Conditioning, Classical/physiology; Fear; Male; Maze Learning/drug effects; Mice; Mice, Transgenic; Muscarinic Antagonists/pharmacology; Polymers/chemistry; Rats; Rats, Inbred F344; Reflex, Startle/physiology; Scopolamine/pharmacology; Solubility

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Collection: 01-internacional Database: MEDLINE Main subject: Brain / Aging / Amyloid beta-Peptides / Maze Learning Type of study: Prognostic_studies Limits: Animals Language: En Journal: Behav Brain Res Year: 2006 Type: Article Affiliation country: United States

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