Angiogenic Proteins/metabolism; Brain Neoplasms/physiopathology; Cerebral Veins/physiopathology; Growth Substances/metabolism; Hemangioma, Cavernous, Central Nervous System/physiopathology; Neovascularization, Pathologic/physiopathology; Adolescent; Adult; Aged; Angiogenic Proteins/genetics; Brain Neoplasms/genetics; Brain Neoplasms/metabolism; Cerebral Veins/abnormalities; Cerebral Veins/pathology; Child; Child, Preschool; Disease Progression; Endothelial Cells/metabolism; Endothelial Cells/pathology; Female; Growth Substances/genetics; Hemangioma, Cavernous, Central Nervous System/genetics; Hemangioma, Cavernous, Central Nervous System/metabolism; Humans; Inheritance Patterns/genetics; Ki-67 Antigen/metabolism; Male; Middle Aged; Neovascularization, Pathologic/genetics; Neovascularization, Pathologic/metabolism; Platelet-Derived Growth Factor/metabolism; Proto-Oncogene Proteins c-bcl-2/metabolism; Tenascin/metabolism; Transforming Growth Factor beta/metabolism; Up-Regulation/physiology; Vascular Endothelial Growth Factor A/metabolism