Focal adhesion kinase targeting using in vivo short interfering RNA delivery in neutral liposomes for ovarian carcinoma therapy.

Halder, Jyotsnabaran; Kamat, Aparna A; Landen, Charles N; Han, Liz Y; Lutgendorf, Susan K; Lin, Yvonne G; Merritt, William M; Jennings, Nicholas B; Chavez-Reyes, Arturo; Coleman, Robert L; Gershenson, David M; Schmandt, Rosemarie; Cole, Steven W; Lopez-Berestein, Gabriel; Sood, Anil K

Halder, Jyotsnabaran; Kamat, Aparna A; Landen, Charles N; Han, Liz Y; Lutgendorf, Susan K; Lin, Yvonne G; Merritt, William M; Jennings, Nicholas B; Chavez-Reyes, Arturo; Coleman, Robert L; Gershenson, David M; Schmandt, Rosemarie; Cole, Steven W; Lopez-Berestein, Gabriel; Sood, Anil K.

Affiliation

Halder J; Department of Gynecologic Oncology, University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.

Clin Cancer Res ; 12(16): 4916-24, 2006 Aug 15.

Article in En | MEDLINE | ID: mdl-16914580

Subject(s)

Focal Adhesion Protein-Tyrosine Kinases/antagonists & inhibitors; Focal Adhesion Protein-Tyrosine Kinases/genetics; Liposomes/administration & dosage; Ovarian Neoplasms/enzymology; Ovarian Neoplasms/therapy; RNA, Small Interfering/administration & dosage; Animals; Apoptosis/drug effects; Cell Proliferation/drug effects; Down-Regulation; Female; Humans; Mice; Mice, Nude; Neovascularization, Pathologic/therapy; Ovarian Neoplasms/blood supply; Ovarian Neoplasms/genetics; Phosphatidylcholines/administration & dosage; RNA, Small Interfering/genetics; Xenograft Model Antitumor Assays

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / RNA, Small Interfering / Focal Adhesion Protein-Tyrosine Kinases / Liposomes Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2006 Type: Article Affiliation country: United States

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