Inhibitory effects of berberine against morphine-induced locomotor sensitization and analgesic tolerance in mice.

Yoo, J-H; Yang, E-M; Cho, J-H; Lee, J-H; Jeong, S M; Nah, S-Y; Kim, H-C; Kim, K-W; Kim, S-H; Lee, S-Y; Jang, C-G

Yoo, J-H; Yang, E-M; Cho, J-H; Lee, J-H; Jeong, S M; Nah, S-Y; Kim, H-C; Kim, K-W; Kim, S-H; Lee, S-Y; Jang, C-G.

Affiliation

Yoo JH; Department of Pharmacology, College of Pharmacy, Sungkyunkwan University, Suwon 440-746, Republic of Korea.

Neuroscience ; 142(4): 953-61, 2006 Nov 03.

Article in En | MEDLINE | ID: mdl-16934942

Subject(s)

Berberine/pharmacology; Brain/drug effects; Drug Tolerance/physiology; Morphine Dependence/drug therapy; Morphine/antagonists & inhibitors; Motor Activity/drug effects; Animals; Berberine/chemistry; Brain/metabolism; Brain/physiopathology; Disease Models, Animal; Dopamine/metabolism; Female; Glutamic Acid/metabolism; Male; Mice; Mice, Inbred ICR; Molecular Structure; Morphine/adverse effects; Morphine Dependence/physiopathology; Motor Activity/physiology; Narcotics/adverse effects; Oocytes; Protein Subunits/drug effects; Protein Subunits/metabolism; Receptors, Dopamine D1/drug effects; Receptors, Dopamine D1/metabolism; Receptors, N-Methyl-D-Aspartate/drug effects; Receptors, N-Methyl-D-Aspartate/metabolism; Synaptic Transmission/drug effects; Synaptic Transmission/physiology; Xenopus

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Collection: 01-internacional Database: MEDLINE Main subject: Berberine / Brain / Drug Tolerance / Morphine / Morphine Dependence / Motor Activity Limits: Animals Language: En Journal: Neuroscience Year: 2006 Type: Article

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