Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs.

Hunt, Mary C; Rautanen, Anna; Westin, Maria A K; Svensson, L Thomas; Alexson, Stefan E H

Hunt, Mary C; Rautanen, Anna; Westin, Maria A K; Svensson, L Thomas; Alexson, Stefan E H.

Affiliation

Hunt MC; Karolinska Institutet, Department of Laboratory Medicine, Division of Clinical Chemistry C1-74, Karolinska University Hospital at Huddinge, Stockhold SE-141 86, Sweden. mary.hunt@ki.se

FASEB J ; 20(11): 1855-64, 2006 Sep.

Article in En | MEDLINE | ID: mdl-16940157

Subject(s)

Evolution, Molecular; Multigene Family; Peroxisomes/enzymology; Thiolester Hydrolases/genetics; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; DNA Primers; Humans; Mice; Molecular Sequence Data; Open Reading Frames; Palmitoyl-CoA Hydrolase/genetics; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Sequence Homology, Amino Acid; Transcription, Genetic

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Collection: 01-internacional Database: MEDLINE Main subject: Thiolester Hydrolases / Multigene Family / Evolution, Molecular / Peroxisomes Limits: Animals / Humans Language: En Journal: FASEB J Journal subject: BIOLOGIA / FISIOLOGIA Year: 2006 Type: Article Affiliation country: Sweden

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