Preferential involvement of Tim-3 in the regulation of hepatic CD8+ T cells in murine acute graft-versus-host disease.

Oikawa, Tsunekazu; Kamimura, Yosuke; Akiba, Hisaya; Yagita, Hideo; Okumura, Ko; Takahashi, Hiroki; Zeniya, Mikio; Tajiri, Hisao; Azuma, Miyuki

Oikawa, Tsunekazu; Kamimura, Yosuke; Akiba, Hisaya; Yagita, Hideo; Okumura, Ko; Takahashi, Hiroki; Zeniya, Mikio; Tajiri, Hisao; Azuma, Miyuki.

Affiliation

Oikawa T; Department of Molecular Immunology, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8549, Japan.

J Immunol ; 177(7): 4281-7, 2006 Oct 01.

Article in En | MEDLINE | ID: mdl-16982862

Subject(s)

Graft vs Host Disease/immunology; Immune Tolerance; Liver Transplantation/immunology; Lymphocyte Activation/immunology; Receptors, Virus/immunology; T-Lymphocytes/immunology; Animals; Antibodies, Monoclonal; CD4 Antigens/immunology; CD4 Antigens/metabolism; CD8 Antigens/immunology; CD8 Antigens/metabolism; Dendritic Cells/immunology; Dendritic Cells/metabolism; Disease Models, Animal; Female; Fluorescent Antibody Technique; Hepatitis A Virus Cellular Receptor 2; Interferon-gamma/biosynthesis; Liver/cytology; Liver/immunology; Macrophages/immunology; Macrophages/metabolism; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Spleen/cytology; Spleen/immunology; Transfection

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Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Virus / Lymphocyte Activation / T-Lymphocytes / Liver Transplantation / Graft vs Host Disease / Immune Tolerance Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Immunol Year: 2006 Type: Article Affiliation country: Japan

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