Accumbal neurons that are activated during cocaine self-administration are spared from inhibitory effects of repeated cocaine self-administration.

Peoples, Laura L; Kravitz, Alexxai V; Lynch, Kevin G; Cavanaugh, Daniel J

Peoples, Laura L; Kravitz, Alexxai V; Lynch, Kevin G; Cavanaugh, Daniel J.

Affiliation

Peoples LL; Department of Psychology, University of Pennsylvania, Philadelphia, PA 19106, USA. lpeoples@psych.upenn.edu

Neuropsychopharmacology ; 32(5): 1141-58, 2007 May.

Article in En | MEDLINE | ID: mdl-17019407

Subject(s)

Cocaine-Related Disorders/physiopathology; Cocaine/adverse effects; Neural Inhibition/drug effects; Neurons/drug effects; Nucleus Accumbens/drug effects; Action Potentials/drug effects; Adaptation, Physiological/drug effects; Animals; Disease Models, Animal; Dopamine/metabolism; Dopamine Uptake Inhibitors/adverse effects; Exploratory Behavior/drug effects; Male; Models, Neurological; Neuronal Plasticity/drug effects; Neurons/metabolism; Nucleus Accumbens/metabolism; Nucleus Accumbens/physiopathology; Rats; Rats, Long-Evans; Self Administration; Synaptic Transmission/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Cocaine / Cocaine-Related Disorders / Neural Inhibition / Neurons / Nucleus Accumbens Type of study: Prognostic_studies Limits: Animals Language: En Journal: Neuropsychopharmacology Journal subject: NEUROLOGIA / PSICOFARMACOLOGIA Year: 2007 Type: Article Affiliation country: United States

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