Endothelial cell anergy is mediated by bFGF through the sustained activation of p38-MAPK and NF-kappaB inhibition.

Flati, V; Pastore, L I; Griffioen, A W; Satijn, S; Toniato, E; D'Alimonte, I; Laglia, E; Marchetti, P; Gulino, A; Martinotti, S

Flati, V; Pastore, L I; Griffioen, A W; Satijn, S; Toniato, E; D'Alimonte, I; Laglia, E; Marchetti, P; Gulino, A; Martinotti, S.

Affiliation

Flati V; Department of Experimental Medicine, University of L'Aquila, L'Aquila, Italy. flativ@univaq.it

Int J Immunopathol Pharmacol ; 19(4): 761-73, 2006.

Article in En | MEDLINE | ID: mdl-17166398

Subject(s)

Clonal Anergy/physiology; Endothelium, Vascular/immunology; Fibroblast Growth Factor 2/physiology; NF-kappa B/antagonists & inhibitors; p38 Mitogen-Activated Protein Kinases/metabolism; Cell Line; Down-Regulation/physiology; Endothelium, Vascular/enzymology; Endothelium, Vascular/metabolism; Enzyme Activation; Humans; Intercellular Adhesion Molecule-1/genetics; Phosphorylation; RNA, Messenger/genetics; Tumor Necrosis Factor-alpha/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Endothelium, Vascular / Fibroblast Growth Factor 2 / NF-kappa B / Clonal Anergy / P38 Mitogen-Activated Protein Kinases Limits: Humans Language: En Journal: Int J Immunopathol Pharmacol Journal subject: ALERGIA E IMUNOLOGIA / FARMACOLOGIA / PATOLOGIA Year: 2006 Type: Article Affiliation country: Italy

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