Outcome of patients with acute promyelocytic leukemia failing to front-line treatment with all-trans retinoic acid and anthracycline-based chemotherapy (PETHEMA protocols LPA96 and LPA99): benefit of an early intervention.

Esteve, J; Escoda, L; Martín, G; Rubio, V; Díaz-Mediavilla, J; González, M; Rivas, C; Alvarez, C; González San Miguel, J D; Brunet, S; Tomás, J F; Tormo, M; Sayas, M J; Sánchez Godoy, P; Colomer, D; Bolufer, P; Sanz, M A

Esteve, J; Escoda, L; Martín, G; Rubio, V; Díaz-Mediavilla, J; González, M; Rivas, C; Alvarez, C; González San Miguel, J D; Brunet, S; Tomás, J F; Tormo, M; Sayas, M J; Sánchez Godoy, P; Colomer, D; Bolufer, P; Sanz, M A.

Affiliation

Esteve J; Hospital Clínic, Barcelona, Spain. jesteve@clinic.ub.es

Leukemia ; 21(3): 446-52, 2007 Mar.

Article in En | MEDLINE | ID: mdl-17205057

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Leukemia, Promyelocytic, Acute/drug therapy; Salvage Therapy; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols/administration & dosage; Biomarkers, Tumor/blood; Child; Child, Preschool; Combined Modality Therapy; Cytarabine/administration & dosage; Etoposide/administration & dosage; Female; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin/administration & dosage; Kaplan-Meier Estimate; Leukemia, Promyelocytic, Acute/blood; Leukemia, Promyelocytic, Acute/mortality; Leukemia, Promyelocytic, Acute/pathology; Leukemia, Promyelocytic, Acute/surgery; Liposomes/administration & dosage; Male; Middle Aged; Mitoxantrone/administration & dosage; Neoplasm, Residual; Oncogene Proteins, Fusion/blood; Prognosis; Recurrence; Remission Induction; Survival Analysis; Time Factors; Treatment Outcome; Tretinoin/administration & dosage

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Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Promyelocytic, Acute / Antineoplastic Combined Chemotherapy Protocols / Salvage Therapy Type of study: Clinical_trials / Guideline / Prognostic_studies Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2007 Type: Article Affiliation country: Spain

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