Predominance of a proinflammatory phenotype in monocyte-derived macrophages from subjects with low plasma HDL-cholesterol.

Sarov-Blat, Lea; Kiss, Robert S; Haidar, Bassam; Kavaslar, Nihan; Jaye, Michael; Bertiaux, Melissa; Steplewski, Klaudia; Hurle, Mark R; Sprecher, Dennis; McPherson, Ruth; Marcel, Yves L

Sarov-Blat, Lea; Kiss, Robert S; Haidar, Bassam; Kavaslar, Nihan; Jaye, Michael; Bertiaux, Melissa; Steplewski, Klaudia; Hurle, Mark R; Sprecher, Dennis; McPherson, Ruth; Marcel, Yves L.

Affiliation

Sarov-Blat L; University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario, K1Y 4W7, Canada.

Arterioscler Thromb Vasc Biol ; 27(5): 1115-22, 2007 May.

Article in En | MEDLINE | ID: mdl-17322100

Subject(s)

Cholesterol, HDL/deficiency; Gene Expression; Hypolipoproteinemias/blood; Macrophages/metabolism; PPAR delta/genetics; PPAR gamma/genetics; RNA/genetics; Atherosclerosis/blood; Atherosclerosis/etiology; Biomarkers/blood; Cholesterol, HDL/blood; Fatty Acid-Binding Proteins/biosynthesis; Fatty Acid-Binding Proteins/genetics; Genotype; Humans; Hypolipoproteinemias/complications; Hypolipoproteinemias/genetics; Interleukin-1beta/biosynthesis; Interleukin-1beta/genetics; Interleukin-8/biosynthesis; Interleukin-8/genetics; Membrane Proteins/biosynthesis; Membrane Proteins/genetics; Microarray Analysis; Mutation; PPAR delta/biosynthesis; PPAR gamma/biosynthesis; Perilipin-2; Phenotype; Polymerase Chain Reaction; Risk Factors; Tumor Necrosis Factor-alpha/biosynthesis; Tumor Necrosis Factor-alpha/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: RNA / Gene Expression / PPAR delta / PPAR gamma / Hypolipoproteinemias / Cholesterol, HDL / Macrophages Type of study: Etiology_studies / Risk_factors_studies Limits: Humans Language: En Journal: Arterioscler Thromb Vasc Biol Journal subject: ANGIOLOGIA Year: 2007 Type: Article Affiliation country: Canada

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