Molecular basis of the isoform-specific ligand-binding affinity of inositol 1,4,5-trisphosphate receptors.

Iwai, Miwako; Michikawa, Takayuki; Bosanac, Ivan; Ikura, Mitsuhiko; Mikoshiba, Katsuhiko

Iwai, Miwako; Michikawa, Takayuki; Bosanac, Ivan; Ikura, Mitsuhiko; Mikoshiba, Katsuhiko.

Affiliation

Iwai M; Division of Molecular Neurobiology, Department of Basic Medical Sciences, Institute of Medical Science, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.

J Biol Chem ; 282(17): 12755-64, 2007 Apr 27.

Article in En | MEDLINE | ID: mdl-17327232

Subject(s)

Amino Acid Substitution; Inositol 1,4,5-Trisphosphate Receptors/chemistry; Inositol 1,4,5-Trisphosphate/chemistry; Animals; Inositol 1,4,5-Trisphosphate/metabolism; Inositol 1,4,5-Trisphosphate Receptors/genetics; Inositol 1,4,5-Trisphosphate Receptors/metabolism; Kinetics; Ligands; Mice; Protein Binding/genetics; Protein Isoforms/chemistry; Protein Isoforms/genetics; Protein Isoforms/metabolism; Protein Structure, Tertiary/genetics; Structure-Activity Relationship

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Collection: 01-internacional Database: MEDLINE Main subject: Inositol 1,4,5-Trisphosphate / Amino Acid Substitution / Inositol 1,4,5-Trisphosphate Receptors Limits: Animals Language: En Journal: J Biol Chem Year: 2007 Type: Article Affiliation country: Japan

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