Inhibition of hepatocarcinoma and tumor metastasis to liver by gene therapy with recombinant CBD-HepII polypeptide of fibronectin.

Liu, Yi; Huang, Bo; Yuan, Ye; Gong, Wei; Xiao, Han; Li, Dong; Yu, Zhi-Rui; Wu, Feng-Hua; Zhang, Gui-Mei; Feng, Zuo-Hua

Liu, Yi; Huang, Bo; Yuan, Ye; Gong, Wei; Xiao, Han; Li, Dong; Yu, Zhi-Rui; Wu, Feng-Hua; Zhang, Gui-Mei; Feng, Zuo-Hua.

Affiliation

Liu Y; Department of Biochemistry and Molecular Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, People's Republic of China.

Int J Cancer ; 121(1): 184-92, 2007 Jul 01.

Article in En | MEDLINE | ID: mdl-17330234

Subject(s)

Carcinoma, Hepatocellular/genetics; Carcinoma, Hepatocellular/therapy; Fibronectins/metabolism; Genetic Therapy; Heparin/metabolism; Peptides/metabolism; Recombinant Proteins/metabolism; Amino Acid Motifs; Animals; Binding Sites; Carcinoma, Hepatocellular/metabolism; Carcinoma, Hepatocellular/pathology; Cell Line, Tumor; Female; Fibronectins/genetics; Gene Expression Regulation, Neoplastic; Humans; Integrin alphaVbeta3/metabolism; Matrix Metalloproteinase 9/metabolism; Mice; Neoplasm Invasiveness/pathology; Neoplasm Metastasis/pathology; Neovascularization, Pathologic/pathology; Peptides/genetics; Recombinant Proteins/genetics; Survival Rate

Search on Google

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Recombinant Proteins / Heparin / Genetic Therapy / Fibronectins / Carcinoma, Hepatocellular Limits: Animals / Female / Humans Language: En Journal: Int J Cancer Year: 2007 Type: Article

Search on Google

XML

PubMed Links