Beta 2-microglobulin gene is mutated in a human colon cancer cell line (HCT) deficient in the expression of HLA class I antigens on the cell surface.

Gattoni-Celli, S; Kirsch, K; Timpane, R; Isselbacher, K J

Gattoni-Celli, S; Kirsch, K; Timpane, R; Isselbacher, K J.

Affiliation

Gattoni-Celli S; Massachusetts General Hospital Cancer Center, Boston.

Cancer Res ; 52(5): 1201-4, 1992 Mar 01.

Article in En | MEDLINE | ID: mdl-1737380

Subject(s)

Colonic Neoplasms/genetics; DNA/genetics; Histocompatibility Antigens Class I/analysis; Mutation/genetics; beta 2-Microglobulin/genetics; Base Sequence; Colonic Neoplasms/immunology; Humans; Immunoglobulin Heavy Chains/isolation & purification; Molecular Sequence Data; Precipitin Tests; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: DNA / Histocompatibility Antigens Class I / Beta 2-Microglobulin / Colonic Neoplasms / Mutation Limits: Humans Language: En Journal: Cancer Res Year: 1992 Type: Article

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