Bax mutation and overexpression inversely correlate with immature phenotype and prognosis of childhood germ cell tumors.

Addeo, Raffaele; Crisci, Stefania; D'Angelo, Velia; Vincenzi, Bruno; Casale, Fiorina; Pettinato, Guido; Donofrio, Vittoria; Boldrini, Renata; Alaggio, Rita; Collini, Paola; Bertorelle, Roberta; Di Tullio, Maria Teresa; Caraglia, Michele; Terenziani, Monica; Lo Curto, Margherita; Indolfi, Paolo

Addeo, Raffaele; Crisci, Stefania; D'Angelo, Velia; Vincenzi, Bruno; Casale, Fiorina; Pettinato, Guido; Donofrio, Vittoria; Boldrini, Renata; Alaggio, Rita; Collini, Paola; Bertorelle, Roberta; Di Tullio, Maria Teresa; Caraglia, Michele; Terenziani, Monica; Lo Curto, Margherita; Indolfi, Paolo.

Affiliation

Addeo R; Pediatric Oncology Service, Pediatric Department, II University of Naples, Naples, Italy.

Oncol Rep ; 17(5): 1155-61, 2007 May.

Article in En | MEDLINE | ID: mdl-17390059

Subject(s)

Mutation; Neoplasms, Germ Cell and Embryonal/genetics; bcl-2-Associated X Protein/genetics; Adolescent; Child; Child, Preschool; Female; Genes, p53; Humans; Immunochemistry; Infant; Infant, Newborn; Male; Neoplasms, Germ Cell and Embryonal/metabolism; Neoplasms, Germ Cell and Embryonal/pathology; Phenotype; Prognosis; Retrospective Studies; Tumor Suppressor Protein p53/biosynthesis; Tumor Suppressor Protein p53/genetics; bcl-2-Associated X Protein/biosynthesis

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Collection: 01-internacional Database: MEDLINE Main subject: Neoplasms, Germ Cell and Embryonal / Bcl-2-Associated X Protein / Mutation Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male / Newborn Language: En Journal: Oncol Rep Journal subject: NEOPLASIAS Year: 2007 Type: Article Affiliation country: Italy

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