Distinct roles of vascular endothelial growth factor-D in lymphangiogenesis and metastasis.

Kopfstein, Lucie; Veikkola, Tanja; Djonov, Valentin G; Baeriswyl, Vanessa; Schomber, Tibor; Strittmatter, Karin; Stacker, Steven A; Achen, Marc G; Alitalo, Kari; Christofori, Gerhard

Kopfstein, Lucie; Veikkola, Tanja; Djonov, Valentin G; Baeriswyl, Vanessa; Schomber, Tibor; Strittmatter, Karin; Stacker, Steven A; Achen, Marc G; Alitalo, Kari; Christofori, Gerhard.

Affiliation

Kopfstein L; Institute of Biochemistry and Genetics, Department of Clinical-Biological Sciences, University of Basel, Center of Biomedicine, Mattenstrasse 28, CH-4058 Basel, Switzerland.

Am J Pathol ; 170(4): 1348-61, 2007 Apr.

Article in En | MEDLINE | ID: mdl-17392173

Subject(s)

Lymphangiogenesis/physiology; Neoplasm Metastasis/physiopathology; Vascular Endothelial Growth Factor D/physiology; Animals; Cells, Cultured; Female; Genotype; Humans; Immunoblotting; Leukocytes/metabolism; Leukocytes/pathology; Lung Neoplasms/genetics; Lung Neoplasms/physiopathology; Lung Neoplasms/secondary; Lymph Nodes/metabolism; Lymph Nodes/pathology; Lymphangiogenesis/genetics; Lymphatic Vessels/metabolism; Lymphatic Vessels/pathology; Lymphatic Vessels/ultrastructure; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Neoplasm Metastasis/genetics; Neovascularization, Pathologic/genetics; Neovascularization, Pathologic/physiopathology; Pancreatic Neoplasms/blood supply; Pancreatic Neoplasms/pathology; Pancreatic Neoplasms/ultrastructure; Rats; Recombinant Fusion Proteins/genetics; Recombinant Fusion Proteins/metabolism; Recombinant Fusion Proteins/physiology; Vascular Endothelial Growth Factor D/genetics; Vascular Endothelial Growth Factor D/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vascular Endothelial Growth Factor D / Lymphangiogenesis / Neoplasm Metastasis Type of study: Prognostic_studies Language: En Journal: Am J Pathol Year: 2007 Type: Article Affiliation country: Switzerland

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