Nuclear corepressor is required for inhibition of phosphoenolpyruvate carboxykinase expression by tumor necrosis factor-alpha.

Yan, Jinhua; Gao, Zhanguo; Yu, Gang; He, Qing; Weng, Jianping; Ye, Jianping

Yan, Jinhua; Gao, Zhanguo; Yu, Gang; He, Qing; Weng, Jianping; Ye, Jianping.

Affiliation

Yan J; Department of Endocrinology, The First-Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510080, China.

Mol Endocrinol ; 21(7): 1630-41, 2007 Jul.

Article in En | MEDLINE | ID: mdl-17456789

Subject(s)

Nuclear Proteins/metabolism; Phosphoenolpyruvate Carboxykinase (GTP)/antagonists & inhibitors; Repressor Proteins/metabolism; Tumor Necrosis Factor-alpha/pharmacology; Animals; Base Sequence; Cell Line, Tumor; Cyclic AMP/metabolism; Cyclic AMP Response Element-Binding Protein/metabolism; DNA Primers/genetics; Hepatocytes/drug effects; Hepatocytes/metabolism; Histone Deacetylases/metabolism; Humans; I-kappa B Kinase/metabolism; I-kappa B Proteins/metabolism; NF-KappaB Inhibitor alpha; NF-kappa B/metabolism; Nuclear Receptor Co-Repressor 1; Phosphoenolpyruvate Carboxykinase (GTP)/genetics; Phosphoenolpyruvate Carboxykinase (GTP)/metabolism; Promoter Regions, Genetic; RNA, Messenger/genetics; RNA, Messenger/metabolism; Rats; Signal Transduction; Transcription, Genetic

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Collection: 01-internacional Database: MEDLINE Main subject: Phosphoenolpyruvate Carboxykinase (GTP) / Repressor Proteins / Nuclear Proteins / Tumor Necrosis Factor-alpha Limits: Animals / Humans Language: En Journal: Mol Endocrinol Journal subject: BIOLOGIA MOLECULAR / ENDOCRINOLOGIA Year: 2007 Type: Article Affiliation country: China

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