p38alpha suppresses normal and cancer cell proliferation by antagonizing the JNK-c-Jun pathway.

Hui, Lijian; Bakiri, Latifa; Mairhorfer, Andreas; Schweifer, Norbert; Haslinger, Christian; Kenner, Lukas; Komnenovic, Vukoslav; Scheuch, Harald; Beug, Hartmut; Wagner, Erwin F

Hui, Lijian; Bakiri, Latifa; Mairhorfer, Andreas; Schweifer, Norbert; Haslinger, Christian; Kenner, Lukas; Komnenovic, Vukoslav; Scheuch, Harald; Beug, Hartmut; Wagner, Erwin F.

Affiliation

Hui L; Research Institute of Molecular Pathology, A-1030 Vienna, Austria.

Nat Genet ; 39(6): 741-9, 2007 Jun.

Article in En | MEDLINE | ID: mdl-17468757

Subject(s)

Cell Proliferation; JNK Mitogen-Activated Protein Kinases/metabolism; Liver Neoplasms, Experimental/metabolism; Liver/embryology; Mitogen-Activated Protein Kinase 14/physiology; Proto-Oncogene Proteins c-jun/metabolism; Animals; Erythrocytes/cytology; Erythrocytes/metabolism; Erythrocytes/pathology; Female; Gene Expression Profiling; Immunoenzyme Techniques; JNK Mitogen-Activated Protein Kinases/genetics; Liver/cytology; Liver/metabolism; Liver Neoplasms, Experimental/pathology; Male; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 14/genetics; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Proteins c-jun/antagonists & inhibitors; Proto-Oncogene Proteins c-jun/genetics; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction

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Collection: 01-internacional Database: MEDLINE Main subject: Proto-Oncogene Proteins c-jun / JNK Mitogen-Activated Protein Kinases / Mitogen-Activated Protein Kinase 14 / Cell Proliferation / Liver / Liver Neoplasms, Experimental Limits: Animals Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2007 Type: Article Affiliation country: Austria

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