Differences in binding of (99m)Tc-disintegrins to integrin alphavbeta3 on tumor and vascular cells.

Knight, Linda C; Romano, Jan E; Cosenza, Stephen C; Iqbal, Nabisa M; Marcinkiewicz, Cezary

Knight, Linda C; Romano, Jan E; Cosenza, Stephen C; Iqbal, Nabisa M; Marcinkiewicz, Cezary.

Affiliation

Knight LC; Radiology Department, Temple University School of Medicine, Philadelphia, PA 19140, USA. lknight@temple.edu

Nucl Med Biol ; 34(4): 371-81, 2007 May.

Article in En | MEDLINE | ID: mdl-17499726

Subject(s)

Disintegrins/chemical synthesis; Integrin alphaVbeta3/metabolism; Muscle, Smooth, Vascular/cytology; Muscle, Smooth, Vascular/metabolism; Organotechnetium Compounds/chemical synthesis; Radiopharmaceuticals; Binding, Competitive/drug effects; Cell Line, Tumor; Disintegrins/pharmacokinetics; Endothelial Cells/metabolism; Humans; Isotope Labeling; Ligands; Organotechnetium Compounds/pharmacokinetics; Radioligand Assay; Radiopharmaceuticals/pharmacokinetics; Receptors, Cell Surface/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Organotechnetium Compounds / Disintegrins / Radiopharmaceuticals / Integrin alphaVbeta3 / Muscle, Smooth, Vascular Limits: Humans Language: En Journal: Nucl Med Biol Journal subject: BIOLOGIA / MEDICINA NUCLEAR Year: 2007 Type: Article Affiliation country: United States

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