Immunophenotypic changes of human articular chondrocytes during monolayer culture reflect bona fide dedifferentiation rather than amplification of progenitor cells.

Diaz-Romero, Jose; Nesic, Dobrila; Grogan, Shawn Patrick; Heini, Paul; Mainil-Varlet, Pierre

Diaz-Romero, Jose; Nesic, Dobrila; Grogan, Shawn Patrick; Heini, Paul; Mainil-Varlet, Pierre.

Affiliation

Diaz-Romero J; Osteoarticular Research Group, Institute of Pathology, University of Bern, Bern, Switzerland.

J Cell Physiol ; 214(1): 75-83, 2008 Jan.

Article in En | MEDLINE | ID: mdl-17559082

Subject(s)

Cartilage, Articular/cytology; Cell Proliferation; Chondrocytes/cytology; Chondrocytes/immunology; Immunophenotyping; Mesenchymal Stem Cells/cytology; Adolescent; Adult; Aggrecans/metabolism; Antibodies, Monoclonal/metabolism; Biomarkers/metabolism; Cadaver; Cell Culture Techniques; Cell Differentiation; Cells, Cultured; Collagen Type I/metabolism; Collagen Type II/metabolism; Cryopreservation; Femur/cytology; Flow Cytometry; Fluorescein-5-isothiocyanate/metabolism; Fluorescent Dyes/metabolism; Humans; Knee Joint/cytology; Lipopolysaccharide Receptors/metabolism; Middle Aged; RNA, Messenger/metabolism; RNA, Ribosomal, 18S/metabolism; Thy-1 Antigens/metabolism; Versicans/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Cartilage, Articular / Immunophenotyping / Chondrocytes / Cell Proliferation / Mesenchymal Stem Cells Limits: Adolescent / Adult / Humans / Middle aged Language: En Journal: J Cell Physiol Year: 2008 Type: Article Affiliation country: Switzerland

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