Tumor targeting of doxorubicin by anti-MT1-MMP antibody-modified PEG liposomes.

Hatakeyama, Hiroto; Akita, Hidetaka; Ishida, Emi; Hashimoto, Koichi; Kobayashi, Hideo; Aoki, Takanori; Yasuda, Junko; Obata, Kenichi; Kikuchi, Hiroshi; Ishida, Tatsuhiro; Kiwada, Hiroshi; Harashima, Hideyoshi

Hatakeyama, Hiroto; Akita, Hidetaka; Ishida, Emi; Hashimoto, Koichi; Kobayashi, Hideo; Aoki, Takanori; Yasuda, Junko; Obata, Kenichi; Kikuchi, Hiroshi; Ishida, Tatsuhiro; Kiwada, Hiroshi; Harashima, Hideyoshi.

Affiliation

Hatakeyama H; Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Hokkaido 060-0812, Japan.

Int J Pharm ; 342(1-2): 194-200, 2007 Sep 05.

Article in En | MEDLINE | ID: mdl-17583453

Subject(s)

Antibiotics, Antineoplastic/therapeutic use; Doxorubicin/therapeutic use; Matrix Metalloproteinase 14/immunology; Animals; Antibiotics, Antineoplastic/administration & dosage; Antibodies, Monoclonal/chemistry; Antibodies, Monoclonal/pharmacology; Doxorubicin/administration & dosage; Drug Compounding; Drug Delivery Systems; Excipients; Immunochemistry; Immunoglobulin Fab Fragments/chemistry; Liposomes; Male; Mice; Mice, Inbred BALB C; Neoplasms, Experimental/drug therapy; Neoplasms, Experimental/metabolism; Polyethylene Glycols/chemistry

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Collection: 01-internacional Database: MEDLINE Main subject: Doxorubicin / Matrix Metalloproteinase 14 / Antibiotics, Antineoplastic Limits: Animals Language: En Journal: Int J Pharm Year: 2007 Type: Article Affiliation country: Japan

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