Lipopolysaccharide (LPS) directly suppresses growth hormone receptor (GHR) expression through MyD88-dependent and -independent Toll-like receptor-4/MD2 complex signaling pathways.

Dejkhamron, Prapai; Thimmarayappa, Jamuna; Kotlyarevska, Kateryna; Sun, Jinhong; Lu, Chunxia; Bonkowski, Erin L; Denson, Lee A; Menon, Ram K

Dejkhamron, Prapai; Thimmarayappa, Jamuna; Kotlyarevska, Kateryna; Sun, Jinhong; Lu, Chunxia; Bonkowski, Erin L; Denson, Lee A; Menon, Ram K.

Affiliation

Dejkhamron P; Department of Pediatrics, University of Michigan, Ann Arbor, MI, USA.

Mol Cell Endocrinol ; 274(1-2): 35-42, 2007 Aug 15.

Article in En | MEDLINE | ID: mdl-17601656

Subject(s)

Gene Expression Regulation; Lipopolysaccharides/metabolism; Lymphocyte Antigen 96/metabolism; Myeloid Differentiation Factor 88/metabolism; Receptors, Somatotropin/metabolism; Signal Transduction/physiology; Toll-Like Receptor 4/metabolism; Animals; Cell Line; Genes, Reporter; Humans; Lipopolysaccharide Receptors/metabolism; Lymphocyte Antigen 96/genetics; Mice; Multiprotein Complexes; Myeloid Differentiation Factor 88/genetics; Promoter Regions, Genetic; Receptors, Somatotropin/genetics; Toll-Like Receptor 4/genetics

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Somatotropin / Signal Transduction / Gene Expression Regulation / Lipopolysaccharides / Lymphocyte Antigen 96 / Toll-Like Receptor 4 / Myeloid Differentiation Factor 88 Limits: Animals / Humans Language: En Journal: Mol Cell Endocrinol Year: 2007 Type: Article Affiliation country: United States

Fulltext

XML

PubMed Links

Search on Google