Topology and sequence in the folding of a TIM barrel protein: global analysis highlights partitioning between transient off-pathway and stable on-pathway folding intermediates in the complex folding mechanism of a (betaalpha)8 barrel of unknown function from B. subtilis.

Forsyth, William R; Bilsel, Osman; Gu, Zhenyu; Matthews, C Robert

Forsyth, William R; Bilsel, Osman; Gu, Zhenyu; Matthews, C Robert.

Affiliation

Forsyth WR; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, 364 Plantation Street, Worcester, MA, 01605, USA.

J Mol Biol ; 372(1): 236-53, 2007 Sep 07.

Article in En | MEDLINE | ID: mdl-17619021

Subject(s)

Bacillus subtilis; Bacterial Proteins/chemistry; Protein Folding; Amino Acid Sequence; Anisotropy; Bacillus subtilis/genetics; Kinetics; Models, Molecular; Molecular Sequence Data; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Temperature

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Collection: 01-internacional Database: MEDLINE Main subject: Bacillus subtilis / Bacterial Proteins / Protein Folding Language: En Journal: J Mol Biol Year: 2007 Type: Article Affiliation country: United States

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