Increased immunogenicity of recombinant Ad35-based malaria vaccine through formulation with aluminium phosphate adjuvant.

Ophorst, Olga J A E; Radosevic, Katarina; Klap, Jaco M; Sijtsma, Jeroen; Gillissen, Gert; Mintardjo, Ratna; van Ooij, Mark J M; Holterman, Lennart; Companjen, Arjen; Goudsmit, Jaap; Havenga, Menzo J E

Ophorst, Olga J A E; Radosevic, Katarina; Klap, Jaco M; Sijtsma, Jeroen; Gillissen, Gert; Mintardjo, Ratna; van Ooij, Mark J M; Holterman, Lennart; Companjen, Arjen; Goudsmit, Jaap; Havenga, Menzo J E.

Affiliation

Ophorst OJ; Crucell Holland BV, P.O. Box 2048, 2301 CA Leiden, The Netherlands. o.ophorst@Crucell.com

Vaccine ; 25(35): 6501-10, 2007 Aug 29.

Article in En | MEDLINE | ID: mdl-17646036

Subject(s)

Adenoviridae/immunology; Adjuvants, Immunologic/pharmacology; Aluminum Compounds/pharmacology; Malaria Vaccines/immunology; Phosphates/pharmacology; Adjuvants, Immunologic/chemistry; Aluminum Compounds/chemistry; Animals; Antibody Formation/immunology; Cell Survival; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Female; Flow Cytometry; Fluorescent Antibody Technique, Indirect; Genetic Vectors; Immunity, Cellular/immunology; Immunization, Secondary; Malaria Vaccines/chemistry; Mice; Mice, Inbred BALB C; Phosphates/chemistry; Reverse Transcriptase Polymerase Chain Reaction; Vaccines, Synthetic/chemistry; Vaccines, Synthetic/immunology

Search on Google

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Phosphates / Adenoviridae / Adjuvants, Immunologic / Malaria Vaccines / Aluminum Compounds Limits: Animals Language: En Journal: Vaccine Year: 2007 Type: Article Affiliation country: Netherlands

Search on Google

XML

PubMed Links