Selecting highly affine and well-expressed TCRs for gene therapy of melanoma.

Jorritsma, Annelies; Gomez-Eerland, Raquel; Dokter, Maarten; van de Kasteele, Willeke; Zoet, Yvonne M; Doxiadis, Ilias I N; Rufer, Nathalie; Romero, Pedro; Morgan, Richard A; Schumacher, Ton N M; Haanen, John B A G

Jorritsma, Annelies; Gomez-Eerland, Raquel; Dokter, Maarten; van de Kasteele, Willeke; Zoet, Yvonne M; Doxiadis, Ilias I N; Rufer, Nathalie; Romero, Pedro; Morgan, Richard A; Schumacher, Ton N M; Haanen, John B A G.

Affiliation

Jorritsma A; Department of Immunology, the Netherlands Cancer Institute (NKI), Amsterdam, The Netherlands.

Blood ; 110(10): 3564-72, 2007 Nov 15.

Article in En | MEDLINE | ID: mdl-17660381

Subject(s)

Genetic Therapy/methods; Melanoma/therapy; Receptors, Antigen, T-Cell/genetics; Receptors, Antigen, T-Cell/metabolism; Animals; Female; Gene Expression Regulation, Neoplastic; Gene Transfer Techniques; Humans; Immunotherapy, Adoptive; Jurkat Cells; K562 Cells; Melanoma/genetics; Melanoma/pathology; Mice; Mice, Inbred C57BL; Substrate Specificity; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Antigen, T-Cell / Genetic Therapy / Melanoma Type of study: Evaluation_studies Limits: Animals / Female / Humans Language: En Journal: Blood Year: 2007 Type: Article Affiliation country: Netherlands

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