Analysis of hepatic metabolism affecting pharmacokinetics of propranolol in humans.

Kiriyama, A; Honbo, A; Iga, K

Kiriyama, A; Honbo, A; Iga, K.

Affiliation

Kiriyama A; Department of Pharmacokinetics, Faculty of Pharmaceutical Sciences, Doshisha Women's College of Liberal Arts, Kodo, Kyotanabe, Kyoto 610-0395, Japan. akiriyam@dwc.doshisha.ac.jp

Int J Pharm ; 349(1-2): 53-60, 2008 Feb 12.

Article in En | MEDLINE | ID: mdl-17765415

Subject(s)

Adrenergic beta-Antagonists/pharmacokinetics; Liver/metabolism; Propranolol/pharmacokinetics; Adrenergic beta-Antagonists/blood; Animals; Area Under Curve; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Male; Microsomes, Liver/metabolism; Models, Biological; Propranolol/blood; Rats; Rats, Wistar; Tissue Distribution

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Collection: 01-internacional Database: MEDLINE Main subject: Propranolol / Adrenergic beta-Antagonists / Liver Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Int J Pharm Year: 2008 Type: Article Affiliation country: Japan

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