Novel cytotoxic T-lymphocyte escape mutation by a three-amino-acid insertion in the human immunodeficiency virus type 1 p6Pol and p6Gag late domain associated with drug resistance.

Cao, Jianhong; McNevin, John; McSweyn, Matthew; Liu, Yi; Mullins, James I; McElrath, M Juliana

Cao, Jianhong; McNevin, John; McSweyn, Matthew; Liu, Yi; Mullins, James I; McElrath, M Juliana.

Affiliation

Cao J; Fred Hutchinson Cancer Research Center, D3-100, 1100 Fairview Avenue North, Seattle, WA 98109, USA.

J Virol ; 82(1): 495-502, 2008 Jan.

Article in En | MEDLINE | ID: mdl-17942528

Subject(s)

Epitopes, T-Lymphocyte/genetics; HIV-1/drug effects; HIV-1/immunology; T-Lymphocytes, Cytotoxic/immunology; gag Gene Products, Human Immunodeficiency Virus/genetics; Anti-HIV Agents/pharmacology; Epitopes, T-Lymphocyte/immunology; HIV Infections/immunology; HIV Infections/virology; HIV-1/genetics; Humans; Longitudinal Studies; Mutagenesis, Insertional; Protein Structure, Tertiary; gag Gene Products, Human Immunodeficiency Virus/chemistry; gag Gene Products, Human Immunodeficiency Virus/immunology; pol Gene Products, Human Immunodeficiency Virus/chemistry; pol Gene Products, Human Immunodeficiency Virus/genetics; pol Gene Products, Human Immunodeficiency Virus/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes, Cytotoxic / HIV-1 / Epitopes, T-Lymphocyte / Gag Gene Products, Human Immunodeficiency Virus Type of study: Observational_studies / Risk_factors_studies Limits: Humans Language: En Journal: J Virol Year: 2008 Type: Article Affiliation country: United States

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