A study of 17beta-estradiol-regulated genes in the vagina of postmenopausal women with vaginal atrophy.

Cotreau, Monette M; Chennathukuzhi, Vargheese M; Harris, Heather A; Han, Lixin; Dorner, Andrew J; Apseloff, Glen; Varadarajan, Usha; Hatstat, Ellyn; Zakaria, Marjorie; Strahs, Andrew L; Crabtree, Judy S; Winneker, Richard C; Jelinsky, Scott A

Cotreau, Monette M; Chennathukuzhi, Vargheese M; Harris, Heather A; Han, Lixin; Dorner, Andrew J; Apseloff, Glen; Varadarajan, Usha; Hatstat, Ellyn; Zakaria, Marjorie; Strahs, Andrew L; Crabtree, Judy S; Winneker, Richard C; Jelinsky, Scott A.

Affiliation

Cotreau MM; Discovery Translational Medicine, Wyeth Research, Cambridge, MA, United States.

Maturitas ; 58(4): 366-76, 2007 Dec 20.

Article in En | MEDLINE | ID: mdl-17997058

Subject(s)

Climacteric/genetics; Estradiol/administration & dosage; Gene Expression Regulation/drug effects; Vagina/pathology; Administration, Cutaneous; Adult; Aged; Atrophy; Biopsy; Cell Differentiation/drug effects; Cell Differentiation/genetics; Climacteric/drug effects; Cornified Envelope Proline-Rich Proteins; Desmoglein 1/genetics; Epithelium/drug effects; Epithelium/pathology; Estradiol/blood; Female; Follicle Stimulating Hormone/blood; Humans; Hydrogen-Ion Concentration; Matrix Metalloproteinase 10/genetics; Membrane Proteins/genetics; Middle Aged; Oligonucleotide Array Sequence Analysis; RNA, Messenger/genetics; Receptors, CXCR6; Receptors, Chemokine; Receptors, Virus; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic/drug effects; Vagina/drug effects; Vagina/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Vagina / Climacteric / Gene Expression Regulation / Estradiol Type of study: Prognostic_studies Limits: Adult / Aged / Female / Humans / Middle aged Language: En Journal: Maturitas Year: 2007 Type: Article Affiliation country: United States

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